http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1317440-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8adf1aa119f2fa8c92dc31e5ef07b387 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D309-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| filingDate | 2001-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0934651cc804c4778bd13e8f2e8091ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d10185dfaa976b66bd30a0b6c025a5d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8ecf583cc4d41ae51e236416f38cd4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ad36b50c743be9f6a49f9d0a4d8ced5 |
| publicationDate | 2006-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1317440-B1 |
| titleOfInvention | Process for the preparation of 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivatives |
| abstract | The invention relates to the preparation of 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivatives of formula 1, where X stands for a leaving group, and R 1 , R 2 , and R 3 each independently stand for an alkyl group with 1-3 carbon atoms from 4-hydroxy-6-X-substituted-methyl-tetrahydropyran-2-one compounds, where X is as defined above, with the aid of an acetalization agent, in the presence of an acid catalyst. The invention also relates to the novel compounds of formula 1 as well as salts and acids to be prepared from these, with the OR 3 group in formula 1 being replaced by an OY group, where X, R 1 and R 2 have the meanings defined above and where Y stands for an alkaline (earth) metal or a substituted or unsubstituted ammonium group or stands for hydrogen, and to the novel compounds of formula 2. The products concerned are, after conversion into the t-butyl ester of 2-(6-hydroxymethyl-1,3-dioxane-4-yl)acetic acid, important as intermediary products in the preparation of statins. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014203045-A1 |
| priorityDate | 2000-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.