http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1315690-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c086fffa81bcd43852d9f8abbbab9243 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C243-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B20-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
filingDate | 2001-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9b9547f05b1d98ebe756d178b82056c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d21f201d34997e5c136ebc578c31f0a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fa3273b02cee06e0a273919f0b6e049 |
publicationDate | 2003-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1315690-A2 |
titleOfInvention | Generation of combinatorial libraries and assessment thereof by deconvolution |
abstract | The present invention deals with a method for the generation of a dynamic combinatorial library of ligands for a given target, capable of binding at least two functionalities, which method comprises the following steps: (i) selecting a set of n molecules carrying functionalities which may bind to the target, which molecules are capable of reversibly binding to each other under formation of an entity, n being an integer ≥ 1; (ii) mixing together said set of said n molecules; (iii) subjecting the mixture to conditions allowing a reversible bond formation and cleavage under formation of entities carrying different combinations of functionalities, until equilibrium is reached; (iv) optionally transforming the said entities into ligands; (v) repeating steps (i) to (iv) n-times, each time a different molecule of said set of n molecules being omitted; (vi) assessing the ability of each of the mixtures obtained to bind to a given target. |
priorityDate | 2000-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 201.