http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1312680-A1

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-023
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filingDate 2001-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f60285536debbeb0e3f5b6fd4cba308e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08d02053957001f510a2df7f7d764b68
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publicationDate 2003-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1312680-A1
titleOfInvention Process for the synthesis of all-D-peptides and peptide nucleic acids
abstract (a) Bereitstellen einer Aminokomponente, wobei die Aminokomponente aus mindestensneiner D-Aminosäure, bevorzugter Weise einem all-D-Polypeptid besteht, (b) Bereitstellen der Carboxykomponente, wobei die Carboxykomponente einenAbgangsgruppe umfasst und aus mindestens einer D-Aminosäure, bevorzugter Weiseneinem all-D-Polypeptid besteht, und (c) Umsetzen der Aminokomponente und der Carboxykomponente mit dem Enzym unternAusbildung einer Peptidbindung zwischen der Aminokomponente und dernCarboxykomponente und unter Abspaltung der Abgangsgruppe von dernCarboxykomponente, wobei das all-D-Polypeptid erhalten wird. n The present invention relates to a method for the synthesis of an all-D polypeptide using an enzyme comprising the steps: (a) providing an amino component, the amino component consisting of at least one D-amino acid, preferably an all-D polypeptide, (b) providing the carboxy component, the carboxy component comprising a leaving group and consisting of at least one D-amino acid, preferably an all-D polypeptide, and (c) reacting the amino component and the carboxy component with the enzyme to form a peptide bond between the amino component and the carboxy component and to separate the leaving group from the carboxy component, whereby the all-D polypeptide is obtained.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015074756-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9238676-B2
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9999650-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10272132-B2
priorityDate 2001-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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