abstract |
The present invention provides uses of a polypeptide having a ligand activity tona sensory epithelium neuropeptide-like receptor (SENR) which is a G protein-couplednreceptor protein, and a DNA encoding the same. More specifically, the presentninvention provides an anti-attention-deficit-disorder or anti-narcolepsy agent, whichncomprises a polypeptide having a ligand activity for SENR or a salt thereof, as well as anmethod for screening compounds having an anti-attention-deficit-disorder ornanti-narcolepsy activity or compounds having an anti-anxiety, anti-depression,nanti-insomnia, anti-schizophrenia or anti-fear activity or salts thereof, which comprisesnusing the above polypeptide or a precursor protein of the polypeptide or a salt thereof. |