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filingDate 2000-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a61a0c6b6597e9f944aae1b1bb6f0911
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publicationDate 2003-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1308092-A1
titleOfInvention Method of constructing gene manipulation animal and clone animal
abstract A genetically engineered cloned animal is created by synchronizing the cellncycle of an embryonic stem cell on which genetic engineering has been performed tonmetaphase, transplanting the nucleus of this cell to the cytoplasm of an enucleatednunfertilized ovum, and activating the transplanted nucleus. An animal created by thisnmethod is useful as a model animal for various diseases.
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