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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_623b0392df5a9519b669d4dd07dedaad
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publicationDate 2003-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1305061-A1
titleOfInvention Ocular plug for punctal and intracanalicular implants
abstract An ocular plug design and method of insertion is described for the treatment of dry eye. This ocular plug is a narrow rod-like cylinder of appropriate diameter, which is tapered at one end, for insertion into an ocular channel. The plug is prepared from either (or both) of two specific classes of polymeric materials having both viscous and elastic properties. The first class of polymeric materials have a glass transition temperature (Tg) at or below human body temperature (37 DEG C). The second class of polymeric materials have a melting temperature (Tm) at or below human body temperature (37 DEG C). The plug is stored in a frozen, rigid, elongated state prior to insertion into an ocular channel. Once inserted into an ocular channel, the smart plug responds to an increase in temperature, due to the surrounding physiochemical environment, whereby it becomes soft and the plug subsequently expands to adapt to the size and shape of the patient's punctum or canaliculum. Once the plug expands to the size of the particular ocular channel, the plug is met with a resistance from the surrounding tissue. At this point, expansion of the plug ceases and the plug can effectively block tear drainage through either ocular channel.
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