| abstract |
The present invention relates to a method of screening a drug by using andisease-associated gene product, an antibody to the disease-associated gene product,nan antisense DNA that suppresses the expression of the disease-associated gene, etc. n A compound regulating the activity of a protein having an amino acidnsequence which is the same or substantially the same amino acid sequence as thenamino acid sequence represented by SEQ ID NO:1, or its salt, a neutralizing antibodynregulating the activity of the above protein, an antisense DNA, etc. can regulate thenexpression of the protein having an amino acid sequence which is the same ornsubstantially the same amino acid sequence as the amino acid sequence representednby SEQ ID NO: 1 and, therefore, are usable as preventive/therapeutic agents forndiseases, e.g., heart diseases, etc. |