Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620ecb9324409347c27e96b6071503ee |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-26 |
filingDate |
2001-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7cdb4293a65e8981c13c5d489024453 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_289423fd317963a779c9626faa513f53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_205e54099c836c0a026ccea4eb2b22cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee28820b93eeac3edbc07d4ca3494b25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1372bb2f1fd8a16f011296102707acac |
publicationDate |
2003-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1295595-A1 |
titleOfInvention |
Tablet rapidly disintegrating in mouth and process for producing the same |
abstract |
The present invention pertains to a quick disintegrating tablet in buccal cavity,ncharacterized in that drug-containing particles with a mean particle diameter ofnapproximately 50 to approximately 250 µm and an apparent specific gravity of approximatelyn0.5 to approximately 1.2 consisting of a bitter tasting drug and/or drug of inferior fluidity andna pharmaceutical preparation carrier and obtained by spray drying are added to a quickndisintegrating tablet in buccal cavity comprising a drug and saccharide. Moreover, thenpresent invention pertains to a method for manufacturing drug-containing particles having anspecific mean particle diameter and specific apparent gravity by dissolving and suspending anbitter tasting drug and/or drug of inferior fluidity and a pharmaceutical preparation carriern(preferably containing water-insoluble polymer, particularly at least aqueous ethyl cellulosensuspension (preferably containing plasticizer)) to a high concentration in terms of solidnconcentration in a solvent that is pharmaceutically acceptable and then spray drying thisnliquid using a rotating disk-type spray dryer, with the disk operating at low speed, and anmethod for manufacturing a quick disintegrating tablet in buccal cavity comprising saidnparticles. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8663684-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010071593-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9987376-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I426921-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9675549-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104902877-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007071240-A1 |
priorityDate |
2000-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |