Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d00c4b6ccbd5a737d8660933064c5f99 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-5601 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01R33-465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-465 |
filingDate |
2001-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7d9817076aeca97b2d39a922a6abfc1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_560a90186f89be8adbaccbf15d48566c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93915e3036e9e44576f765a593799cfe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2d4986c896e074cb74cec05ebda040d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e5750823133fa10d723cabd8dd560c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fca11c58f43bd2367389a5757d57f9d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44a6098ac1621def683f3822f39c6226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b977d5a6a904bc72ad2d620924d21063 |
publicationDate |
2003-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1290461-A1 |
titleOfInvention |
Method for investigating the fate of a test compound or the state of a biological system by means of nmr of hyperpolarised nmr active nuclei |
abstract |
The invention is concerned with Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI), particularly NMR spectroscopy. It provides hyperpolarisation methods offering enhanced sensitivity of detection over conventional NMR for studying the fate of a test compound in a biological system. The methods are particularly suitable for studying metabolism and toxicity of drugs. The resulting NMR sensitivity increase is advantageous in two key aspects of NMR detection: test compounds can be detected at lower concentrations and substantial time saving can be achieved in cases where extensive averaging is conventionally employed to increase the signal to noise ratio of the corresponding NMR spectra. The methods can be used for studios that were not practical or not possible using conventional NMR. |
priorityDate |
2000-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |