| abstract |
This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula (I) wherein one of X, Y or Z is independently -S-,-0- CH2- or ⊃N-R6, the others are -CH¿2?-; m is an integer from 0 to 3 inclusive; n is an integer from 1 to 6 inclusive; R?4¿ is (C¿1-6?)-alkyl; R?5¿ is independently in each occurrence (C¿1-6?)-alkyl, (C1-6)-alkenyl, (C1-6)- alkynyl or cycloalkyl; and R?1, R2, and R3¿ are hydrogen or specified substituents. These compounds are useful for treating diseases associated with smooth muscle disorders. |