| abstract |
A 7-substituted fused ring tetracycline compound of formula (I): nwherein: nX nis CR 6 R 6' ; nR 4 nand R 4' are each alkyl; nR 5 nis hydrogen, hydroxyl, or a prodrug moiety; nR 6 and R 6' nare each independently hydrogen, hydroxyl, alkyl, or taken together, alkenyl; nY and Y' nare each independently optionally substituted C, N, O, or S; nm nis 1 or 2; or a pharmaceutically acceptable salt thereof. |