http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1286939-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| filingDate | 2001-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8a75af8e4794a0319961392bcfa6bb7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21a4c3f64e9f5c7e1136132ff675be78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b71968d2c9ae762303b1ac40bb27591 |
| publicationDate | 2003-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1286939-A1 |
| titleOfInvention | Method for fluoromethylation of alcohols via halogenative decarboxylation |
| abstract | A method for fluoromethylation of an alcohol via halogenative decarboxylation. The method includes the step of reacting an alcohol of the formula R1C(CX3)2OH with an alpha- haloester of the formula X2CH2CO2R2 to form an alpha-alkoxy ester, wherein R1 is selected from the group consisting of hydrogen and alkyl groups, wherein R2 is selected from the group consisting of hydrogen and alkyl groups, wherein X, at each occurrence, is independently selected from the group consisting of hydrogen, bromine, fluorine, and chlorine, and wherein X2 is selected from the group consisting of bromine and chlorine. The resulting alpha-alkoxy ester is saponified to form an alpha-alkoxy acid which is heated at reflux with lead tetraacetate and a chlorinating agent to form a chloride compound of the formula R1C(CX3)2OCH2Cl. The chloride compound is converted to a fluoride compound of the formula R1C(CX3)2OCH2F with a fluorinating agent. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7376460-B2 |
| priorityDate | 2000-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.