| abstract |
The present invention provides an excellentnacetylcholinesterase inhibitor. That is, it provides annacetylcholinesterase inhibitor comprising a 1-benzylpyridiniumnsalt represented by the following formula:n nwherein R 1 , R 2 , R 3 and R 4 are the same as or different from eachnother and each represents a hydrogen atom, a halogen atom, anhydroxyl group, a nitrile group, a C 1-6 alkyl group, a C 1-6 alkoxyngroup etc.; R 5 represents a hydrogen atom, a halogen atom etc.;nthe partial structure:n nis a group represented by the formula >C(R 6 )-CH 2 - (wherein R 6 nis a hydrogen atom or a halogen atom) or >C=CH-; X - representsna halide ion or organic sulfonic acid ion; and m is 0 or an integernfrom 1 to 5. |