| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_724d6ab649531b448ad9b8cd9966b5e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c8eafa661d66872a6fc2bb489fbb9d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate |
2002-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fa010123ce4e9fca23b3c28204190c9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc4360bf5e77b5f33a7d3df1109f3c1d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aa04e29cf8b53c378978bedc2d009a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a77947403cf7ed41ccb9937e534c34bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_826716eb5ba743da0319e7c3e7f63c12 |
| publicationDate |
2003-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1283200-A2 |
| titleOfInvention |
Optically pure paroxetine precursors |
| abstract |
A biocatalytic process to obtain optically enrichednderivatives of trans-4-(4-fluorophenyl)-3-hydroxymethylpiperidines,nbased on the enzymatic resolution ofnracemic precursors of formula III (where R 3 is preferablynphenyl or benzyl) by acylation of the hydroxyl group.nDepending on the enzyme and the reaction conditions, either ofnthe two enantiomers may be obtained with high enantiomericnpurity. These compounds are important intermediates in thensynthesis of the paroxetine anti-depressive agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1431287-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2228274-A1 |
| priorityDate |
2001-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |