| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16 |
| filingDate |
2002-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_300f1c272a6671596104fa8c24a1730d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b66fd4c91d135a0f0ea18e0b8d14d8f |
| publicationDate |
2003-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1273654-A1 |
| titleOfInvention |
BAD as substrate for PP2C |
| abstract |
The invention relates to a combination of a protein phosphatase type 2C as annenzyme and a phospho - BAD as substrate. The protein BAD isndephosphorylated in position Ser 155 . Furthermore, the combination is used in ann in vitro screening for ligands which modulate protein phosphatase type 2C,ncomprising the steps: incubating the protein phosphatase type 2C inncombination with the substrate phospho - BAD and the ligand of the assay andndetecting the decrease in phospho - BAD and / or the increase in phosphate andn/ or BAD. Therefore, new drugs for the treatment apoptosis may be found. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1374862-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1374862-A2 |
| priorityDate |
2001-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |