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filingDate 2001-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4907ee2d1ad8c4e62562bf5c06805da
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publicationDate 2004-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1270579-A4
titleOfInvention PROCESS FOR THE PRODUCTION OF CAMPTOTHECIN
abstract A process for economically producing a large amount of camptothecin which is the starting compound for irinotecan hydrochloride and various camptothecin derivatives, characterized by involving the following steps (a) and (b): (a) the step of hydrolyzing 9-methoxycamptothecin or a natural material containing 9-methoxycamptothecin; and (b) the step of converting the 9-hydroxycamptothecin obtained in the step (a) into a 9-o-perfluoro(lower alkyl)sulfonyl or 9-o-phenyltetarzolyl derivative followed by the hydrogenolysis into camptothecin.
priorityDate 2000-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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