http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1268744-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d21cbff64022f95c237c0bd3ec8656ca |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-29 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-29 |
filingDate | 2001-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de6812594a9502e1da04765288983fcf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4366e915fb6cff40b495d58afa23e226 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_866ffcf25097dd7cf516cc296d4e5f60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_701dff6daba12725fb229f544a3a83ea |
publicationDate | 2003-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1268744-A2 |
titleOfInvention | Rickettsia felis outer membrane protein |
abstract | The present invention is directed to isolated nucleic acid molecules encoding Rickettsia felis outer membrane proteins (R. felis omp). Expression vectors and host cells comprising the nucleic acid momlecules are also provided, as well as methods for increasing or decreasing the expression of R. felis omp in host cells. The invention further provides a method of screening a substance for the ability of the substance to modify R. felis omp function, and a method for isolating other R. felis omp molecules. DNA oligomers capable of hybridizing to the nucleic acid molecule encoding the R. felis omp are provided, which can be used to detect R. felis omp in a sample. An isolated R. felis omp is also provided. Antibodies specific for the protein, and fragments thereof, are provided, as are compositions comprising the protein and a compatible carrier. The subject invention further provides a method of preventing R. felis infections by R. felis present in a carrier host, and a method of reducing R. felis infection of a carrier host. |
priorityDate | 2000-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 279.