| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6c9201213e4a966d85cbcd61f66e805 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6068 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-644
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-092
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-646 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-09 |
| filingDate |
2001-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80e5823607561629e5887bf3519ca108
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6901630ef510e6bbd5688ae2a2c092e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b12a298659497501bdd085417c4569b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f822b96661c3f6231b252bfce192ae67 |
| publicationDate |
2003-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1267938-A1 |
| titleOfInvention |
Proteins for use as carriers in conjugate vaccines |
| abstract |
Vaccine conjugates are described comprising a capsular polysaccharide antigen conjugated to a carrier molecule, which carrier molecule is a protein associated with iron uptake by pathogenic microorganisms. The vaccine conjugate may comprise second or additional antigens also conjugated to the carrier. In a preferred embodiment, the carrier is a transferrin binding protein, in particular TbpA or TbpB. Also described are methods for conjugating the antigen/s to the carrier molecule, and to the use of transferrin binding protein in the manufacture of a carrier-antigen conjugate for vaccination. Affinity matrices comprising immobilised ligand for an iron uptake protein, and the use thereof for purifying a vaccine conjugate according to the present invention are also described. |
| priorityDate |
2000-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |