abstract |
The invention relates to new active recombinantnfusion proteins comprising a luciferase, or a fragment,nor a variant thereof fused to a selection markernprotein, or a fragment or a variant thereof, saidnfusion proteins having at least a light-producingnactivity and a selection marker activity. Thencorresponding polynucleotides, DNA cassettes, vectorsnand kits are claimed. The invention also relates to anmethod of selecting cells into the genome of which angenetic element such as a tag has been targeted into atnleast one predefined locus, and a method for trappingnunknown genes. |