http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1261608-B1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_41443e007b16044e1da9897b0711225c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2000-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2004-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_222fdaf3b4ee038b89f2cc167865fb28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d9197eed16580d26cfd654ac8216c231 |
| publicationDate | 2004-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1261608-B1 |
| titleOfInvention | Diketopiperazine derivatives to inhibit thrombin |
| abstract | The present invention relates to compounds to inhibit blood coagulation, and more particularly to novel diketopiperazine derivatives, pharmaceutically acceptable salts and compositions thereof, to specifically inhibit thrombin. The compound has the following general structure (I), wherein R<1>, R<2> and R<4> consist of a hydrogen, alkyl or aryl moiety, R<3> consist of an alkyl or aryl moiety, wherein R<5> consists of a hydrogen, alkyl, aryl, hydroaryl, heteroaryl, hydroheteroaryl, sulfonylalkyl, sulfonylaryl, sulfonylhydroaryl, sulfonylheteroaryl or sulfonylhydroheteroaryl moiety, and wherein R<6> consists of a hydrogen, alkyl, aryl, hydroaryl, heteroaryl or hydroheteroaryl moiety. Also disclosed are methods of using the compound for treating coagulation disorders such as thrombosis and heparin associated thrombocytopenia. |
| priorityDate | 1999-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 187.