| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9433d383d1922b3df0ca6c182c7d3925 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2000-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d34c9f139a954291c28efd2981b1846d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73f85a12f07feac7e9b0e36eb8fb6f63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81d28d7f695000ba652bc38af45c91e7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1aa5f69343eeeda868b769d9b7f5932
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c25d6cea3fedb32d74aec8125f88e64e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c10255beaf5d497d3ca64c7ccb9e22b8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91a385d810867751c70fb79d03926a88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80bb7fa87737725f93000fad9d9d4f68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10e79a533d34c7a50a8639f75eea4376 |
| publicationDate |
2002-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1259509-A1 |
| titleOfInvention |
Process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo 1,2-a]pyrimidine-3-(n,n-dimethyl-acetamide) and intermediates |
| abstract |
The invention relates to a new and improved process for the preparation of 6-methyl-2-(4-methyl-phenyl)-imidazo[1,2-a]pyrimidine-3-(N,N-dimethyl-acetamide) of Formula (I) and pharmaceutically acceptable acid addition salts thereof which comprises reacting an ester of general Formula (II) (wherein R is lower alkyl or phenyl-lower alkyl) in a polar protic or aprotic solvent with dimethyl amine and, if desired, converting the compound of the Formula (I) thus obtained into a pharmaceutically acceptable acid addition salt. The compound of Formula I is a known valuable sedative used in therapy. The invention also relates to new intermediates of general Formula (II) (wherein R is lower alkyl or phenyl-lower alkyl) useful in the process. |
| priorityDate |
1999-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |