| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27c7356e1b24e58b12842543f3f555c2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 |
| filingDate |
2000-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11922478bf851e01d7cf4d549593be91
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99a98d1d75de62c81a9b81abfe8cad69
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d21d3a8d57e1592e6aab10c25d1addbd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_724c68fbe57936b298e47b386775e267 |
| publicationDate |
2004-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1259263-B1 |
| titleOfInvention |
Complexation of rna, especially ribozymes, with polyethylenimines for the stabilization and cellular introduction thereof |
| abstract |
The invention relates to the complexation of RNA with optionally modified polyethylenimines for extracellular and intracellularin vitro and in vivo stabiliztion thereof and for cellular introduction of the complexed RNA in cells. The invention also relates to chemically modified or non-modified, natural or synthetic ribozymes complexes and polyethylenimine (PEI) having any chain length, molar mass and degree of branching, which is chemically modified or non-chemically modified. The invention further relates to the production of complexes and to the use thereof in the protection of RNA against enzymatic and non-enzymatic degradation and their reception in vitro or in vivo in cells. The biological activity of the ribozymes remains intact. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019177550-A1 |
| priorityDate |
1999-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |