| abstract |
The present invention provides a process for producingnoptically active 3-hydroxy-4-methoxypyrrolidine, which is annintermediate for synthesizing a quinuclidine derivative usefulnas a squalene synthetase inhibitor, a salt thereof, or a hydratenthereof by subjecting a pyrrolidine derivative represented bynthe following formula (1-4):n n wherein R 3a and R 3b are different and each of R 3a and R 3b nrepresents a hydrogen atom or a methyl group, to optical divisionnpurification by using an optically active dibenzoyltartaricnacid derivative or the like. |