| abstract |
It was found that an inducible nitric oxygen synthase (i-NOS) inhibitor is effective for Sj¦gren's syndrome, and based on this knowledge, an agent for treating and/or preventing Sj¦gren's syndrome comprising the i-NOS inhibitor as an active ingredient has been completed. As the i-NOS inhibitor, for example, a condensed piperidine compound represented by formula (I), an acid addition salt thereof or a hydrate thereof is preferably used: <CHEM> wherein symbols in the formula are described in the description. |