abstract |
A biocompatible, resorbable Type II collagen-based matrix is reconstituted from solubilized animal cartilage tissue and used in the culture and growth of cells, such as chondrocyte cells. The matrix is produced by isolating cartilage tissue, solubilizing and reconstituting the cartilage to form a fleece-like material, pressing the fleece-like material to form a sheet-like article, and sterilizing the article. An implantable article for cartilage repair includes chondrocyte cells retained on the matrix. |