| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87e7bafd9928f0f5b53b20a39bed770a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C281-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-17 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C281-18 |
| filingDate |
2001-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1a30dd11e4906cb2591f4e7824dbc58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65e4e18e429e3dab052e88cf8fd71bbf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99304c7ef35ef684df3b0fdc525d1ca8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_25471059fdc937aeb491f8296e7f6b8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10f6195a3a6e10b9edd6849e901ca005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8f3a1902a9374cacbfd2de2514e1d4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b090096cc903ccdad8723fb0c63f022
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4409870c4fc77522e3369922e687280d |
| publicationDate |
2005-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1255541-B1 |
| titleOfInvention |
Aromatic guanylhydrazone for the treatment of resistant viral infections |
| abstract |
The present invention relates to aromatic guanylhydrazone compounds and their use as pharmaceutically active agents, especially for prophylaxis and treatment of virally caused diseases and infections, including opportunistic infections. The inventive guanylhydrazone compounds are also useful as inhibitors of deoxyhypusine synthase and as inhibitors for nuclear export in infectious diseases and may be used to regulate bacterially induced TNF-alpha production. Furthermore, the aromatic guanylhydrazones exhibit antibacterial activity against Gram positive and Gram negative bacteria and can be regarded as a novel class of antibiotics. In addition, methods for prophylaxis and treatment of virally or bacterially induced infections and diseases are disclosed together with pharmaceutical compositions useful within said methods containing at least one aromatic guanylhydrazone of the present invention as active ingredient. |
| priorityDate |
2000-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |