| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f2dc11082d70caa0848fe03e087fb60 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C281-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-17 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C281-18 |
| filingDate |
2001-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2a48c623cbde1bcad1b0ca1fcffc3c4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d805cc38b668ac1f49cd1c547d5e7c0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61b994b3d17a697f09945ae8d9f762a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5012f88ad7bd05ffa818b1072189de48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_293c093d082ec833adf95b5467a65d87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc414203b24d094acab6533225daa115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_361777532fc25a7dc1a809082f5c47c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a8645812a25263db9ffb4d34f4f82ed |
| publicationDate |
2002-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1255541-A2 |
| titleOfInvention |
Pharmaceutically active aromatic guanylhydrazones |
| abstract |
The present invention relates to aromatic guanylhydrazone compounds and their use as pharmaceutically active agents, especially for prophylaxis and treatment of virally caused diseases and infections, including opportunistic infections. The inventive guanylhydrazone compounds are also useful as inhibitors of deoxyhypusine synthase and as inhibitors for nuclear export in infectious diseases and may be used to regulate bacterially induced TNF-alpha production. Furthermore, the aromatic guanylhydrazones exhibit antibacterial activity against Gram positive and Gram negative bacteria and can be regarded as a novel class of antibiotics. In addition, methods for prophylaxis and treatment of virally or bacterially induced infections and diseases are disclosed together with pharmaceutical compositions useful within said methods containing at least one aromatic guanylhydrazone of the present invention as active ingredient. |
| priorityDate |
2000-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |