abstract |
An objective of the present invention is to provide carbapenem derivatives which have potent antibiotic activity against MRSA, PRSP, Influenzavirus, and beta -lactamase-producing bacteria and are stable against DHP-1. The compounds according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts thereof: <CHEM> wherein R<1> represents H or methyl; R<2> and R<3> represent H, a halogen atom, alkyl or the like; and R<4> represents substituted lower alkylthio or the like. |