http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1250430-A2
Outgoing Links
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e1cb764d51b6c001c2deaa376c098587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c4f4d2a32f6a80c56a817f670cec425 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60d78138a3c0fae138728dd9a55d452f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7cbe2f22413f6e5fa117356c2a1a376 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 |
filingDate | 2001-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc123955c6ad199a88abeeb864a6c7b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23ca67df8d3128eec034269e24a7a055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3f5c5d9ef4abe54e44d448b12a9704c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85d41d827fd5deb212b400791eb0dc17 |
publicationDate | 2002-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1250430-A2 |
titleOfInvention | Regulatory sequence for the specific expression in dendritic cells and uses thereof |
abstract | The present invention relates to regulatory sequences which mediate dendritic cell-specific expression. The regulatory sequences are isolated from the human fascin gene and also comprise for instance promoter sequences. Moreover, described are recombinant nucleic acid molecules and vectors which contain the regulatory sequences and as preferred embodiments, recombinant nucleic acid molecules and vectors encoding antigens or immunoregulatory proteins. Furthermore, the invention relates to host cells, which contain the recombinant nucleic acid molecules or vectors, and to methods for their preparation. Other embodiments relate to in vitro methods for stimulating T-cells and for preparing T cell-stimulating dendritic cells and for formulating them as pharmaceutical compositions. Additional pharmaceutical compositions are described which essentially relate to DNA vaccines and gene therapeutic pharmaceutical compositions, for instance for the immunization against and treatment of infectious diseases, tumors, allergies, Creutzfeldt-Jakob plaques or Alzheimer plaques. Additional pharmaceutical compositions according to the invention can be used for targeted, dendritic cell-mediated modulation of immune responses, for instance to treat autoimmune diseases or graft rejection. Moreover, various uses of the regulatory sequences are described. |
priorityDate | 2000-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 721.