abstract |
The present invention relates to a rational, elegantnmeans of producing, loading and using Class I moleculesntherapeutic applications in the treatment of a variety ofnconditions, including cancer, tumors or neoplasias, asnwell as viral, retroviral, autoimmune, and autoimmune-typendiseases. The present invention also relates tonvectors, cell lines, recombinant DNA molecules encodingnhuman β2 microglobulin or Class I MHC molecules innsoluble and insoluble form, and methods of producingnsame. |