abstract |
The present invention relates to the finding that peptides derived from a spccific domain of tumornnecrosis factor-alpha (TNF-α) can efficiently be used to treat oedema. More specifically, thenpresent invention relates to the usage of peptides derived from the region of human TNF-α fromnSer 100 to Glu 116 to treat pulmonary oedema. Moreover, the present invention concerns ancircularized peptide having amino acid sequence CGQRETPEGAEAKPWYC which is verynefficient in inducing oedema resorption. |