abstract |
Nine novel genes sustaining hydrophobic domains, which arenestimated to be seven transmembrane domains characteristic to Gnprotein-coupled receptors, are successfully isolated by humanntissue cDNA screening. These genes and proteins which are thenexpression products thereof are usable in screening ligands,nscreening agonists or antagonists which are useful as drugs,ndiagnosing diseases in which these gene participate, etc. |