| abstract |
The present invention is related to benzazole derivatives according to formula (I) wherein X is O, S, or NR?O with R0¿ being H or an unsubstituted or substituted C¿1?-C6alkyl, and G is an unsubstituted or substituted pyrimidinyl group, notably for use as pharmaceutically active compounds, as well as to pharmaceutical formulations containing such benzazoles derivatives. Said benzazoles derivatives are efficient modulators of the JNK pathway, they are in particular efficient and selective inhibitors of JNK2 and/or 3. |