| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01a96e8bbea00eeaa0b50c2a0c000dba
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e071d18fea054bf8d1420d483e78ed1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9ad271736b5af44ac98b04e055605fb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B6-506 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0448
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D451-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F13-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-0478 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D451-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F13-00 |
| filingDate |
1999-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feca335165689a7fe80a3e2df541c6ee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69dc9810b284a1a0478b1caa356a39d6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7862405bf5c1986681907f8ca7c23cd |
| publicationDate |
2002-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1238978-A2 |
| titleOfInvention |
Intermediates for the synthesis of radiolabelled tropanes |
| abstract |
The compounds of the present invention comprise a tropane compound ornligand that selectively binds to tropane recognition sites, e.g., neuronntransporters such as that DAT. The tropane ligand is radiolabeled with anradioactive technetium or rhenium by a chelating ligand which isnattached to the tropane ligand by a linker. n Tropane compounds or ligands useful in the pratice of the presentninvention can generally be represented by formula II where R 1 nand R 2 are defined as above and where R 1 can also bensubstituted at the C 4 position of the tropane ring:n n Any tropane compound of the general formula II is useful in thenpresent invention so long as it binds to DAT. n Useful tropane analogs have a 3α-group,i.e., are of the boatnconfiguration. Intermediates for the synthesis of the radiolabeledntropanes are claimed. |
| priorityDate |
1999-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |