Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69108fc12b940ede105638f37f06080b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 |
filingDate |
1992-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6592b349dd74664bb06bd97f0b7959d1 |
publicationDate |
2002-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1231265-A2 |
titleOfInvention |
A receptor protein tyrosine kinase |
abstract |
Isolated mammalian nucleic acid molecules encoding receptor protein tyrosine kinasenexpressed in primitive hematopoietic cells and not expressed in mature hemotopoietic cells arenprovided. Also included are the receptors encoded by such nucleic acid molecules; the nucleicnacid molecules encoding receptor protein tyrosine kinases having the sequences shown innFigure 1 (flk-2); the receptor protein tyrosine kinases having the amino acid sequences shownnin Figure 1 (flk-2); ligands for the receptors; nucleic acid sequences that encode the ligands;nmethods of stimulating the proliferation and/or differentiation of primitive mammaliannhematopoietic stem cells comprising contacting the stem cells with a ligand that binds to anreceptor protein tyrosine kinase expressed in primitive mammalian hematopoietic cells and notnexpressed in mature hematopoietic cells and antibodies to the claimed receptor protein tyrosinenkinase flk-2. |
priorityDate |
1991-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |