http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1230230-A1

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filingDate 2000-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_56c1cf180ba3a81c7ad2ae7894980363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c48ccd832050b3cf4d7ab9a8a06882c8
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03980b4f53f8922b4cbfc1a5f30953f2
publicationDate 2002-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1230230-A1
titleOfInvention Indeno-, naphtho-, and benzocyclohepta-dihydrothiazole derivatives, the production thereof and their use as anorectic medicaments
abstract The invention relates to compounds of the formula (I), wherein Y is a direct bond, -CH2-, -CH2-CH2-, X represents CH2, CH(CH3); CH(C2H5), CH(C3H7), CH(C6H5); R4 represents (C8-C16) cycloalkyl, wherein one or more hydrogen(s) can be substituted in the alkyl groups by fluorine or a hydrogen can be substituted by OH, OC(O)CH3, OC(O)H, O-CH2-Ph or O-(C1-C4) alkyl; (CH2)n-A-R8, with n = 1-6, with the group -CH2-O-CH2-phenyl, wherein phenyl is unsubstituted, being excluded; (CH2)r-B-R9, with r = 1-6; A is O, S, SO, SO2; B is NH, N-(C1-C6) alkyl, NCHO, N(CO-CH3); R8 represents (C5-C24) alkyl, (C3-C10) cycloalkyl, wherein one or more hydrogen(s) can be substituted in the alkyl groups by fluorine or hydrogen can be substituted by OH, OC(O)CH3, OC(O)H, O-CH2-Ph or O-(C1-C4) alkyl; (CH2)m aryl, with m = 0-6, and aryl is phenyl, naphthyl, biphenyl, thienyl or pyridyl and the aryl part can be substituted up to two times; R9 represents (CH2)m aryl, with m = 0-6, and aryl is phenyl, naphthyl, biphenyl, thienyl or pyridyl and the aryl part can be substituted up to two times, and wherein the groups R1, R'1, R2 and R3 have the indicated meanings. The invention also relates to the physiologically acceptable salts thereof and to methods for producing them. The inventive compounds are suitable, for example, for use as anorectic agents.
priorityDate 1999-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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