| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10505ee88b23bd710f02ab61c0210d7d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5192
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5123 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 |
| filingDate |
2000-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4178e96e4f4f37b98b4b8a2350c5a48b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95ba51ec388084b419c28e08b5a1ccd8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a76c33fd520bbe283aa79dd596c28779 |
| publicationDate |
2002-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1225871-A2 |
| titleOfInvention |
Method for the formulation of substances having a low water-solubility and lipophilicity and formulation thus obtained |
| abstract |
The present invention relates to a method for encapsulating substances, in particular drugs, that have a low water-solubility and lipophilicity, which method comprises providing a lipid system comprising one or more negatively charged lipid(s); combining the lipid system with the substance(s) in a medium at a low total solutes concentration; subjecting the mixture thus obtained to one or more cycles of freezing and thawing to produce lipid-coated aggregates of the substance(s), and optionally removing the free (non-enclosed) substance(s). The method is in particular suitable for encapsulating cisplatin. |
| priorityDate |
1999-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |