http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1225174-B2

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55
filingDate 2000-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2010-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63fa80d055b171eb27931f56a0fc3a60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90d18c6cb8d2cea248087123223ffbfa
publicationDate 2010-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1225174-B2
titleOfInvention Anhydrous mirtazapine crystals and process for the production thereof
abstract Low-hygroscopic anhydrous mirtazapine crystals having a hygroscopicity of not more than 0.6% by weight when the crystals are stored in the air having a relative humidity of 75% at 25 DEG C under atmospheric pressure for 500 hours; a process for preparing the same; a crystal of a mirtazapine hydrate represented by the formula (I): <CHEM> wherein n is an integer of 1 to 5; and a process for preparing the same. According to the process of the present invention, stable anhydrous mirtazapine crystals having almost no hygroscopic property can be prepared by a convenient industrial process. In addition, since the anhydrous mirtazapine crystals of the present invention have excellent low hygroscopic property, they can be suitably used, for instance, as an antidepressant.
priorityDate 1999-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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