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filingDate 2000-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b9c2ba703f1d2454703b7be73583383
publicationDate 2002-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1224474-A1
titleOfInvention Multiwell scanner and scanning method
abstract A multiwell plate scanner comprises a detector for measuring an attribute of a sample which is scanned continuously over wells of a multiwell plate. A signal obtained during the scan may be sampled and digitized based on detector position over the multiwell plate. The scanner is also disclosed for scanning microarrays, bio-chips and areas of samples not having physical separations. The scanner may be used in a high throughput screening system comprising a storage and retrieval module, a sample distribution module, a reagent distribution module, and a detector which incorporates the scanner. The screening system may further comprise a transport module and a data processing and integration module for transporting samples between the components of the system and for controlling system operation. In a further aspect, the present invention comprises methods and apparatus to compensate for variations, inconsistencies and other differences in the dimensions, configuration and/or materials of the platform in which an assay is performed. Another aspect of the invention is a system and method for performing an assay to detect the effect of a reagent on a target. The present invention is also directed to compositions and therapeutics identified by the disclosed methods. A further aspect of the present invention is a method of testing a therapeutic for therapeutic activity and toxicology by identifying a compound using a method of the present invention and monitoring the toxicology and efficacy of the therapeutic in an in vivo model.
priorityDate 1999-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA0A1S6M1N0
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID31192
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID822234
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID822235
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID565256
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID835828
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID564461
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID822224
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID426118296
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID567181
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID31188
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6610344
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID822230
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID43304
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID35822
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID35837
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID183248
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100535003
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419527025
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45706
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100126610
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID35821
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45556
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID541056
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID35835
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID832559
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID183247
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4804
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCS6BVH1
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID826961
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID179156
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419503687
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID836464
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45524
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID823550
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226394200
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID832383
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID826959
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID823988
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID184472
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID836003
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID184473
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID823990
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID840067
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCV4HJ73
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID824011
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9VV43
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226394314
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID823987
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226411806
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2768720
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID832589
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4363046
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID823989
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID33755
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID823985
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID179550
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID34817
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID832585
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100003342
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID823986
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID33748
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6009037
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID937623
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID33749
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100127346
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID832560
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ14BI2
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID832584
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9SWE3
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID837865
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID45282
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID833619
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14389199
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8H0I7
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID833546
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID824497
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ1ZZH0
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID833607
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9QYS2
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID22880

Total number of triples: 390.