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filingDate 2001-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a79ab4df996caa4f634bb60ed02095b8
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publicationDate 2004-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1219591-B1
titleOfInvention Process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine
abstract The invention relates to a process for preparing 2-(4-trifluoromethoxyphenyl)ethylamine in an advantageous manner by(a) converting trifluoromethoxybenzene by halomethylation into halogenomethyl-1-trifluoromethoxybenzene,(b) converting the halogenomethyl-1-trifluoromethoxybenzene by halogen-cyano exchange into 4-(trifluoromethoxyphenyl)acetonitrile, and(c) reducing the 4-(trifluoromethoxyphenyl)acetonitrile using hydrogen in the presence of a nickel catalyst to form 2-(4-trifluoromethoxyphenyl)ethylamine.The first step of this process also represents an advantageous process for preparing 4-bromomethyl- and 4-chloromethyl-1-trifluoromethoxybenzene.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7605290-B2
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type http://data.epo.org/linked-data/def/patent/Publication

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