http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1218752-A2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_32756b39847909ba7c0492c7ffb26d4b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6803 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-542 |
filingDate | 2000-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17e3131fc63d2c72c5a605c3c926cc4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_045db94255da7018c72be10a56262c94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b004cba47d24b142b6f9eed5b585aa16 |
publicationDate | 2002-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1218752-A2 |
titleOfInvention | Protein fingerprinting by multisite labelling |
abstract | Protein molecules (4a-4c, 10, 10a-10c) of interest are isolated and modified into linearized protein molecules (10, 10a-10c). Individual protein molecules are isolated for observation with hydrodynamic focusing apparatus (130), atomic force microscope (150), a separation plate (170), or the combination of isoelectric focusing gel (180), and electrophoresis gel (184). In the linearized protein molecule (10, 10a-10c) a first type of amino acid residue (K) is labelled with a first tag (12), and a second type of amino acid residue (C) is labelled with a second tag (14). Tags (12, 14) impart a detectable set of distinguishing characteristic ancillary properties (24, 34, 38, 44, 48, 52, 64, 68, 72, 120, 122, 206, 208, 210, 244, 246, 248) to the linearized protein molecule (10, 10a-10c) that define the fingerprint thereof. Protein fingerprints are recovered as images (206, 208, 210, 244, 246, 248) by camera (204) or fluorescence microscope (230), or as spectral analyses (24, 34, 38, 44, 48, 52, 64, 68, 72, 120, 122) by optical detector (15). Compilations of fingerprints for known protein molecules comprise fingerprint libraries to which the fingerprint of a protein molecule of interest is compared. |
priorityDate | 1999-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 252.