| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7268b381f01c4b6da8aa0305ef409186 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2002-82
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2002-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01P2004-12 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y30-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-587
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54373
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-588 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-551
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 |
| filingDate |
2000-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2006-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fd80cc4f4ae237a8732fb93c66a833a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e59792bd0ab324c97ae634f18af22c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8496aa4593e1d94a47febbeb43b1c2a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c4685c5e495cc177e13dc76e11a18d1e |
| publicationDate |
2006-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1210600-B1 |
| titleOfInvention |
Method for detecting bioanalytes using metal nanoshells |
| abstract |
The present invention provides nanoshell particles ("nanoshells") for use in biosensing applications, along with their manner of making and methods of using the nanoshells for <i>in vitro </i> and <i>in vivo</i> detection of chemical and biological analytes, preferably by surface enhanced Raman light scattering. The preferred particles have a non-conducting core and a metal shell surrounding the core. For given core and shell materials, the ratio of the thickness (i.e., radius) of the core to the thickness of the metal shell is determinative of the wavelength of maximum absorbance of the particle. By controlling the relative core and shell thicknesses, biosensing metal nanoshells are fabricated which absorb light at any desired wavelength across the ultraviolet to infrared range of the electromagnetic spectrum. The surface of the particles are capable of inducing an enhanced SERS signal that is characteristic of an analyte of interest. In certain embodiments a biomolecule is conjugated to the metal shell and the SERS signal of a conformational change or a reaction product is detected. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2523027-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102013106432-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9572880-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102013008104-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2343047-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2343047-B1 |
| priorityDate |
1999-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |