Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd5e8b1259c9db4154925eb3ef95e143 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-90245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-968 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-80 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-82 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-82 |
filingDate |
2000-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a31dcd2cd97c6ea3aabf659fedaba73a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf8d07ed7adfce2d9baf7f9ab8eb6d80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a3f2fa764af6df742a5b196e135d520 |
publicationDate |
2002-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1210342-A1 |
titleOfInvention |
The use of fluorescein aryl ethers in high throughput cytochrome p450 inhibition assays |
abstract |
Novel fluorescent substrates of human cytochrome P450 enzymes are provided. Also provided are methods for their manufacture and use. These substrates are useful in assessing cytochrome P450 enzyme activity and in selecting compounds which inhibit cytochrome P450 enzyme activity and, in particular, for identifying potential adverse drug interactions which are mediated by inhibition of cytochrome P450 enzyme activity. |
priorityDate |
1999-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |