http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1207903-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24259cdcadff78fe3351762071cfa45d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61F2-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 2000-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1495c7831f2270da22a768a752c40bf1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74aab90cd51f0366bf0b72d3ff3e3372 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72056ff46ea6ff1b1e49c08449ba15c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5cf08a322c66ae26cd4388dc426c1b47 |
| publicationDate | 2002-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1207903-A1 |
| titleOfInvention | Reduction of the immunogenicity of non-human grafts |
| abstract | The present invention relates to a transplantion material produced by dissociation of porcine tissue and removal of macrophages and/or microglial cells therefrom. The tissue could be an embryonic or fetal neural tissue and the removal could be effected by exposing the preparation above to antibodies against the GalĪ±1-3GalĪ²1-R epitope and a complement reagent. The invention also relates to the use of such a transplantation material for preparing a pharmaceutical preparation useful when transplanting neural tissue. The invention also relates to a kit comprising one or more enzymes for tissue dissociation, an antibody preparation and a complement reagent. The invention also relates to a process for removal of macrophages and/or microglial cells from porcine embryonic or fetal neural tissue. Finally, the invention relates to a process for treatment of neurological disorders with such pretreated porcine neural grafts. |
| priorityDate | 1999-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 262.