| abstract |
The present invention is to provide a stable pharmaceuticalncomposition for oral use and preparation thereof in which changes arenprevented in drug release during storage even under the exposure to light,nby adding yellow ferric oxide and/or red ferric oxide in a matrix typensustained-release preparation containing a drug, a hydrophilic base, andnpolyethylene oxide. The present invention is to further provide a methodnfor preventing changes in drug release during storage under the exposure tonlight in a matrix type sustained-release preparation containing a drug, anhydrophilic base, and polyethylene oxide. The quality assurance period ofnthe product can be prolonged and the product value can be improved by thenpresent invention. |