abstract |
A process for preparing a dibenzothiazepine derivativensuch as dibenzo[b,f] [1,4]thiazepin-11-one employablenas a starting material for the preparation of 11-[4-(2-(2-hydroxyethoxy)ethyl)]-1-piperadinyldiberizothiazepinenderivative which is known to be effective as an antipsychoticnpharmaceutical, has the steps of reacting a nitrobenzenenderivative with a thiosalicylic acid derivative,nreducing the obtained 2-nitro-2'-carboxy-diphenylsulfidenderivative, and subjecting the obtained 2-amino-2'-carboxy-diphenylsulfidenderivative to dehydration-condensationnreaction. |