| abstract |
The present invention provides non-steroidal compounds of Formula I,nincluding prodrugs and pharmaceutically acceptable salts thereof, which arenselective modulators (e.g., agonists, partial agonists and antagonists) of a steroidnreceptor, specifically, the glucocorticoid receptor. The present invention alsonprovides pharmaceutical compositions containing these compounds and methodsnfor using these compounds to treat animals requiring glucocorticoid receptornagonist or antagonist therapy. Glucocorticoid receptor modulators are useful tontreat diseases, such as obesity, diabetes, inflammation and others as describednbelow. The present invention also provides processes for preparing thesencompounds. |