abstract |
A patch formulation for external use where a basic drug,nan organic acid and an organic acid salt are combined asnessential components is disclosed. The basic drug isnpreferably in the form of its acid addition salt. The organicnacid is preferably a carboxylic acid having carbon atoms ofn2 to 7, and more preferably at least one acid selected fromnthe group consisting of acetic, lactic, tartaric, citric,nmalic, benzoic and salicylic acids. The organic acid saltnis preferably a metal salt of a carboxylic acid, and morenpreferably sodium acetate. |