| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_34c531b0dce54fb192c75fd1f4f8d473 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
| filingDate |
2000-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_856708f839f06e0ea727637c5efa626e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99b77794bf9877c56d8ee9629c291715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a30553f3801003efe58c1ad7bff5385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f0afc6859ab8b9554615eddc2cd59dc |
| publicationDate |
2002-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1200095-A1 |
| titleOfInvention |
Medicament with a protective effect against oxidative-toxic substances, particularly against cardiotoxic substances |
| abstract |
The invention relates to the utilization of benzazepine-N-acetic acid derivatives which contain an oxogroup in addition to the nitrogen atom in the alpha position and which are substituted in the third position by a 1-(carboxyalkyl)-cyclopentyl-carbonyl-amino radical and to their salts and biolabile esters for the prophylaxis and/or treatment of heart damages caused by cardiotoxic doses of medicaments or chemicals in large mammals and particularly human beings. The invention particularly relates to the prophylaxis and/or treatment of heart damages, especially myocardial damages, which may occur during cytostatic chemotherapy. The invention further relates to the utilization of the above-mentioned benzazepine-N-acetic acid derivatives for adjuvant treatment in therapies in which medicaments with oxidative-toxic side effects are used. The invention additionally relates to the production of medicaments suitable for said prophylaxis and/or treatment or adjuvant treatment. |
| priorityDate |
1999-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |