Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_869f18e611f82d6b24770c0e2a3973d8 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-44 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22 |
filingDate |
2001-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2004-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad9036bf76ca8d81017f6f847913a687 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5091ffdd03ebe6e7bdde312503391638 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d743a4dfaed3c76e2ef2a6c57a5992b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d52809b3dbbed34d5af764e6ac7b6a04 |
publicationDate |
2004-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1197490-B1 |
titleOfInvention |
Process for preparing N-[1-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride |
abstract |
A process for preparing N-[1- (S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride of the following formula (I), is to react N-[1-(S)-ethyoxy carbonyl-3-phenylpropyl]-L-alanine with XCOOR, wherein X is halogen atom, R is C<sub>1</sub>-C<sub>6</sub> alkyl, to obtain a N-alkoxycarbonyl compound, then reacting with an acyl group activation reagent, finally contact with water. The compound of formula (I) is a key intermediate of ACE inhibitors. |
priorityDate |
2000-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |